entheogens

  • Psychedelic Toad Venom Shows Promise for New Depression Treatment

    Psychedelic Toad Venom Shows Promise for New Depression Treatment

    A potential depression treatment might someday come from trip-inducing toad venom. In a new study Wednesday, researchers appear to have deciphered the structural workings of a psychedelic compound derived from the Colorado River toad (Incilius alvarius). The team also tested a modified version of the compound in mice, finding it had antidepressant and antianxiety effects,…


  • Please Don’t Lick the DMT Toads, Begs the National Park Service

    Please Don’t Lick the DMT Toads, Begs the National Park Service

    If you kiss a frog, you don’t get a prince. But if you lick a Sonoran desert toad (Incilius alvarius, formerly Bufo alvarius) you might have a transformative, quasi-religious psychedelic experience — or you might get sick and die. And either way, the National Park Service is asking that you don’t do it on the…


  • MDMA Therapy for PTSD Looks Safe and Effective in New Trial Data

    MDMA Therapy for PTSD Looks Safe and Effective in New Trial Data

    Follow-up data from a Phase III trial is the latest to suggest that MDMA — also known as ecstasy — could improve mental health when combined with therapy. The study found that MDMA-assisted therapy was better than talk therapy alone in relieving the symptoms of patients with post-traumatic stress disorder, and that this relief remained…